Mechanism of immunocyte therapy

Mechanism of immunocyte therapy

  • 1)Immunocytes to be applied to treatment firstly extracted from patients’ blood or blood components, then put in an exclusive culture fluid and activated with proper agents
  • 2)Retrieve the activated immunocytes from the culture fluid
  • 3)Blend the activated immunocytes and normal saline into drips and then inject into the cancer focus via intravenous fusion or directly

The mechanism that is capable of distinguishing autologous substances from foreign substances such as flu virus, pollen and dust etc., and engulfing or eliminating/discharging the latter or other harmful substances that have invaded the body is inherent and can be referred to as the Immune System that chiefly depends upon leukocytes in the blood stream.

The immune system is also able to cope with abnormal cells that are regarded as precursor of cancer cells and contain proteins (cancer antigen) different from that of normal cells. Manifested in the cell surface, such a cancer antigen is attacked by cytotoxic T cells (CTL) following being recognized as a Cancer Marker and meanwhile, helper T cells can help in this process.

Mechanism of immunocyte therapy PHOTO01

However, for the purpose of not being assaulted, some cancer cells deliberately conceal their markers from the cell surface or decrease their cell-surface-exposure-amount. In such a case, NK cells that are good at preventing infections kick in. As regards autologous cells, they voluntarily present their identity so as to avoid becoming the target of NK cell’s actions. At the same time, NK cells are competent in respect of recognizing antibodies and killing cells that have fused with an antibody, i.e. the Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) Effect that is well-known as a potent mechanism related to antibody medicinal products.